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Mouse monoclonal antibody

Anti-Complement component C4c

CAT NO: CAM 072-18 | Application: ELISA, WB, IP, IHC, IF


Cat. No.

CAM 072-18

Specificity

CAM 072-18 binds human complement factor C4c.

Immunogen

Synthetic peptide consisting of the last 15C-terminal residues of the C4c a4-domain (Cys-EELVYELNPLDHRGR).`

Host

Mouse

Positive Species Reactivity

Human

Negative Species Reactivity

Not determined

Isotype

IgG2b/k

Clone Number

99-72-18

Epitope Specificity

Not determined

Unit Size

400 µL: Cat. No. CAM 072-18-04 1 mL: Cat. No. CAM 072-18-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Protein A/G purified (from culture supernatant)

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Conjugation

Unconjugated BSA free

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

C4c is a compoment in the Complement cascade and is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c (soluble). C4c consists of a g-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa). C4c reacts with C1 and C2 to form C3 convertase of the classic activation pathway.