Mouse monoclonal antibody
Anti-Complement component C4c
CAT NO: CAM 072-18 | Application: ELISA, WB, IP, IHC, IF
Cat. No. |
CAM 072-18 |
---|---|
Specificity |
CAM 072-18 binds human complement factor C4c. |
Immunogen |
Synthetic peptide consisting of the last 15C-terminal residues of the C4c a4-domain (Cys-EELVYELNPLDHRGR).` |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG2b/k |
Clone Number |
99-72-18 |
Epitope Specificity |
Not determined |
Unit Size |
400 µL: Cat. No. CAM 072-18-04 1 mL: Cat. No. CAM 072-18-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
C4c is a compoment in the Complement cascade and is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c (soluble). C4c consists of a g-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa). C4c reacts with C1 and C2 to form C3 convertase of the classic activation pathway. |