Mouse monoclonal antibody

Anti-Complement component C4c

CAT NO: CAM 072-18 | Application: ELISA, WB, IP, IHC, IF

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Cat. No.	CAM 072-18
Specificity	CAM 072-18 binds human complement factor C4c.
Immunogen	Synthetic peptide consisting of the last 15C-terminal residues of the C4c a4-domain (Cys-EELVYELNPLDHRGR).`
Host	Mouse
Positive Species Reactivity	Human
Negative Species Reactivity	Not determined
Isotype	IgG2b/k
Clone Number	99-72-18
Epitope Specificity	Not determined
Unit Size	400 µL: Cat. No. CAM 072-18-04 1 mL: Cat. No. CAM 072-18-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	Protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	C4c is a compoment in the Complement cascade and is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c (soluble). C4c consists of a g-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa). C4c reacts with C1 and C2 to form C3 convertase of the classic activation pathway.