Mouse monoclonal antibody
Anti-Glucagon (human, pig, rat)
CAT NO: ABS 058-08 | Application: ELISA
Cat. No. |
ABS 058-08 |
---|---|
Specificity |
ABS 058-08 binds human glucagon. |
Immunogen |
Synthetic N-terminal fragment of glucagon coupled to carrier |
Host |
Mouse |
Positive Species Reactivity |
Human, Rat, Pig |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
2641, 24952, 397595 |
Clone Number |
8 |
Epitope Specificity |
The epitope lies within the N-terminal half of human glucagon |
Unit Size |
400 µL: Cat. No. ABS 058-08-04 1 mL: Cat. No. ABS 058-08-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Glucagon is a peptide hormone of 29 amino-acid residues produced by the alpha cells of the pancreatic islets. Its effect is to raise blood sugar as a stress hormone and counter-regulatory hormone for insulin. It is produced by cell-type-specific processing of proglucagon, which in the alpha cells is split to form glicentin-related pancreatic polypeptide, glucagon and major proglucagon fragment, while the same precursor is split to form glicentin, oxyntomodulin (C-terminally extended glucagon-37), GLP-1 and GLP-2 in the L cells of the intestinal mucosa. |