Mouse monoclonal antibody

Anti-Pancreatic Polypeptide (human, PP)

CAT NO: ABS 030-06 | Application: ELISA, WB

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Product Summary

Cat. No.
ABS 030-06
Specificity
ABS 030-06 binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1%.
Immunogen
Synthetic human PP
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
5539
Clone Number
6
Epitope Specificity
Not determined
Unit Size
400 µL: Cat. No. ABS 030-06-04 1 mL: Cat. No. ABS 030-06-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Pancreatic polypeptide (PP) is a 36 amino acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.

Application

ELISA: ABS 030-06 binds free PP in solution. ABS 030-06 reacts in ELISA with PP coated directly onto the microtiter well.

WB: ABS 030-06 can be used in Western blotting.

Cat. No.
ABS 030-06
Specificity
ABS 030-06 binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1%.
Immunogen
Synthetic human PP
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
5539
Clone Number
6
Epitope Specificity
Not determined
Unit Size
400 µL: Cat. No. ABS 030-06-04 1 mL: Cat. No. ABS 030-06-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Pancreatic polypeptide (PP) is a 36 amino acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.

ELISA: ABS 030-06 binds free PP in solution. ABS 030-06 reacts in ELISA with PP coated directly onto the microtiter well.

WB: ABS 030-06 can be used in Western blotting.

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