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Mouse monoclonal antibody

Anti-Type III Collagen (human, dog, rat, kangaroo)

CAT NO: CSI 007-01 | Application: ELISA, WB, IHC-F


Cat. No.

CSI 007-01

Specificity

CSI 007-01 is highly specific for type III collagen. It has been shown to have no cross-ractivity with type I and V collagens by ELISA and immunoblotting. There is no evidence for cross-reactivity with other connective tissue proteins (laminin, fibronectin, elastin).

Immunogen

Acid-digested pepsin soluble human type III collagen

Host

Mouse

Positive Species Reactivity

Human, Rat, Dog, Kangaroo

Negative Species Reactivity

Calf, Sheep

Isotype

IgG1/k

Gene ID

1281, 84032, 478835,

Clone Number

1E7-D7/Col3

Epitope Specificity

Epitope is located approximately 100nm from the N-terminal of the molecule

Unit Size

400 µL: Cat. No. CSI 007-01-04 1 mL: Cat. No. CSI 007-01-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Protein A/G purified (from culture supernatant)

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Conjugation

Unconjugated BSA free

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

Type III collagen is present in the walls of arteries, intestines and the uterus, where it strenghtens the connective tissue. Patients with defects in the type III collagen (ex. Ehlers-Danlos syndrome) are at risk of rupture of major arteries or the intestine.