Mouse monoclonal antibody
Anti-Type III Collagen (human, dog, rat, kangaroo)
CAT NO: CSI 007-01 | Application: ELISA, WB, IHC-F

Cat. No. |
CSI 007-01 |
---|---|
Specificity |
CSI 007-01 is highly specific for type III collagen. It has been shown to have no cross-ractivity with type I and V collagens by ELISA and immunoblotting. There is no evidence for cross-reactivity with other connective tissue proteins (laminin, fibronectin, elastin). |
Immunogen |
Acid-digested pepsin soluble human type III collagen |
Host |
Mouse |
Positive Species Reactivity |
Human, Rat, Dog, Kangaroo |
Negative Species Reactivity |
Calf, Sheep |
Isotype |
IgG1/k |
Gene ID |
1281, 84032, 478835, |
Clone Number |
1E7-D7/Col3 |
Epitope Specificity |
Epitope is located approximately 100nm from the N-terminal of the molecule |
Unit Size |
400 µL: Cat. No. CSI 007-01-04 1 mL: Cat. No. CSI 007-01-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Type III collagen is present in the walls of arteries, intestines and the uterus, where it strenghtens the connective tissue. Patients with defects in the type III collagen (ex. Ehlers-Danlos syndrome) are at risk of rupture of major arteries or the intestine. |