Mouse monoclonal antibody
Anti-Procollagen type IIA N-terminal propeptide (human, PIIANP)
CAT NO: BTE 003-02 | Application: ELISA, IHC-P
Cat. No. |
BTE 003-02 |
---|---|
Specificity |
BTE 003-02 is specific for human PIIANP. |
Immunogen |
Recombinant expressed PIIANP |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
1280 |
Clone Number |
2 |
Epitope Specificity |
Epitope is located at the amino-terminal part of procollagen type IIA |
Unit Size |
400 µL: Cat. No. BTE 003-02-04 1 mL: Cat. No. BTE 003-02-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. Procollagen type II N-terminal propeptide (PIIANP) is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30ng/mL. |