DIA HE1 IgE
The DIA HE1 IgE is an affinity-purified, fully human IgE antibody with kappa light chains. It is produced in vitro from a monoclonal hybridoma. This unique source guarantees freedom from contamination by other immunoglobulin isotypes. Compared to IgE from a myeloma patient, where batch-to-batch variability may be high, the monoclonal source of IgE ensures very high reproducibility. This human IgE is used widely in the field of allergy research and diagnostic kit manufacturing, mostly as a standard in quantitative IgE assays and for internal control and QC purposes.
The complement system is a part of the immune system made up of a large number of distinct plasma proteins that react with one another to opsonize pathogens and induce a series of inflammatory responses that help fight infection.
Research in the complement system is of great importance, as complement deficiencies are associated with many autoimmune diseases and recurrent bacterial infections. For example, deficiency in C3, which plays a central role in the activation of the complement system, may lead to life-threatening pyogenic infections, among other diseases.