Mouse monoclonal antibody
Anti-α-calcitonin gene-related peptide (α-CGRP)
CAT NO: ABS 026-05 | Application: ELISA, IHC-P
Cat. No. |
ABS 026-05 |
---|---|
Specificity |
ABS 026-05 binds human α-CGRP. Based on inhibition ELISA, ABS 026-05 shows full cross-reactivity with rat α-CGRP and about 50% cross-reactivity with human b-CGRP. There is no cross-reaction with human amylin. |
Immunogen |
Synthetic human α-CGRP |
Host |
Mouse |
Positive Species Reactivity |
Human, Rat |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
24241 |
Clone Number |
5 |
Epitope Specificity |
The epitope lies within residues 1-18 of human α-CGRP. |
Unit Size |
400 µL: Cat. No. ABS 026-05-04 1 mL: Cat. No. ABS 026-05-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Calcitonin gene-related peptide is a 37 amino acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, In addition to a variety of other cellular effects. |