Mouse monoclonal antibody

Anti-α-calcitonin gene-related peptide (α-CGRP)

CAT NO: ABS 026-05 | Application: ELISA, IHC-P

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Product Summary

Cat. No.
ABS 026-05
Specificity
ABS 026-05 binds human α-CGRP. Based on inhibition ELISA, ABS 026-05 shows full cross-reactivity with rat α-CGRP and about 50% cross-reactivity with human b-CGRP. There is no cross-reaction with human amylin.
Immunogen
Synthetic human α-CGRP
Host
Mouse
Positive Species Reactivity
Human, Rat
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
24241
Clone Number
5
Epitope Specificity
The epitope lies within residues 1-18 of human α-CGRP.
Unit Size
400 µL: Cat. No. ABS 026-05-04 1 mL: Cat. No. ABS 026-05-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Calcitonin gene-related peptide is a 37 amino acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, In addition to a variety of other cellular effects.

Application

ELISA: ABS 026-05 binds free α-CGRP in solution. Based on inhibition ELISA, the affinity of ABS 026-05 is at least 24 times higher than that of ABS 026-04. ABS 026-05 (as capture antibody) forms a sandwich ELISA pair with ABS 026-04 (as biotinylated detection antibody) for measuring human a-CGRP, giving a detection limit of 0.13 nmol/L in an unoptimized buffer assay.

IHC-P: ABS 026-05 works well in IHC on paraffin embedded tissue.

Paraffin embedded rat tissue stained with ABS 026-05 Anti-α-CGRP diluted 1/400 in 1% BSA/PBS and incubated over night.

Cat. No.
ABS 026-05
Specificity
ABS 026-05 binds human α-CGRP. Based on inhibition ELISA, ABS 026-05 shows full cross-reactivity with rat α-CGRP and about 50% cross-reactivity with human b-CGRP. There is no cross-reaction with human amylin.
Immunogen
Synthetic human α-CGRP
Host
Mouse
Positive Species Reactivity
Human, Rat
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
24241
Clone Number
5
Epitope Specificity
The epitope lies within residues 1-18 of human α-CGRP.
Unit Size
400 µL: Cat. No. ABS 026-05-04 1 mL: Cat. No. ABS 026-05-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Calcitonin gene-related peptide is a 37 amino acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, In addition to a variety of other cellular effects.

ELISA: ABS 026-05 binds free α-CGRP in solution. Based on inhibition ELISA, the affinity of ABS 026-05 is at least 24 times higher than that of ABS 026-04. ABS 026-05 (as capture antibody) forms a sandwich ELISA pair with ABS 026-04 (as biotinylated detection antibody) for measuring human a-CGRP, giving a detection limit of 0.13 nmol/L in an unoptimized buffer assay.

IHC-P: ABS 026-05 works well in IHC on paraffin embedded tissue.

Paraffin embedded rat tissue stained with ABS 026-05 Anti-α-CGRP diluted 1/400 in 1% BSA/PBS and incubated over night.

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Product Specification

Non-hazardous statement (SDS)

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Anti-α-calcitonin gene-related peptide (α-CGRP)

CAT. NO. ABS 026-04

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