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Mouse monoclonal antibody

Anti-α-calcitonin gene-related peptide (α-CGRP)

CAT NO: ABS 026-05 | Application: ELISA, IHC-P


Cat. No.

ABS 026-05

Specificity

ABS 026-05 binds human α-CGRP. Based on inhibition ELISA, ABS 026-05 shows full cross-reactivity with rat α-CGRP and about 50% cross-reactivity with human b-CGRP. There is no cross-reaction with human amylin.

Immunogen

Synthetic human α-CGRP

Host

Mouse

Positive Species Reactivity

Human, Rat

Negative Species Reactivity

Not determined

Isotype

IgG1/k

Gene ID

24241

Clone Number

5

Epitope Specificity

The epitope lies within residues 1-18 of human α-CGRP.

Unit Size

400 µL: Cat. No. ABS 026-05-04 1 mL: Cat. No. ABS 026-05-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Protein A/G purified (from culture supernatant)

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Conjugation

Unconjugated BSA free

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

Calcitonin gene-related peptide is a 37 amino acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, In addition to a variety of other cellular effects.