Mouse monoclonal antibody, biotinylated

Anti-H-Ficolin (human)

CAT NO: RIG 334-01B | Application: ELISA

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Product Summary

Cat. No.
RIG 334-01B
Specificity
RIG 334-01 reacts specifically with H-ficolin. No cross-reaction has been observed with L- or M-ficolin.
Immunogen
Recombinant human H-ficolin
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
8547
Clone Number
FCN334
Epitope Specificity
Not determined
Unit Size
150 µL, 1 mg/mL +/- 15%. Cat. No. RIG 334-01B-015 See Certificate of Analysis for details.
Purification
Biotinylated
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Biotin
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.

Application

ELISA: RIG 334-01 reacts with recombinant H-ficolin coated directly onto the microtiter well. A sandwich ELISA for H-ficolin uses RIG 334-01 for both capture and detection. (1)

Scientific References

1. Munthe-Fog L, Hummelshøj T, Ma YJ, Hansen BE, Koch C, Madsen HO, Skjødt K, Garred P (2008) Characterization of a polymorphism in the coding sequence of FCN3 resulting in a Ficolin-3 (Hakata antigen) deficiency state. Molecular Immunology 45:2660-2666.

Cat. No.
RIG 334-01B
Specificity
RIG 334-01 reacts specifically with H-ficolin. No cross-reaction has been observed with L- or M-ficolin.
Immunogen
Recombinant human H-ficolin
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
8547
Clone Number
FCN334
Epitope Specificity
Not determined
Unit Size
150 µL, 1 mg/mL +/- 15%. Cat. No. RIG 334-01B-015 See Certificate of Analysis for details.
Purification
Biotinylated
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Biotin
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.

ELISA: RIG 334-01 reacts with recombinant H-ficolin coated directly onto the microtiter well. A sandwich ELISA for H-ficolin uses RIG 334-01 for both capture and detection. (1)

1. Munthe-Fog L, Hummelshøj T, Ma YJ, Hansen BE, Koch C, Madsen HO, Skjødt K, Garred P (2008) Characterization of a polymorphism in the coding sequence of FCN3 resulting in a Ficolin-3 (Hakata antigen) deficiency state. Molecular Immunology 45:2660-2666.

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Product Specification

Non-hazardous statement (SDS)

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