Mouse monoclonal antibody
Anti-Complement Component C3 (human)
CAT NO: CAM 008-01 | Application: ELISA, Immunoprecipitation (IP), Immunoaffinity Purification (IAP)
Cat. No. |
CAM 008-01 |
---|---|
Specificity |
CAM 008-01 is specific for human complement component 3 (C3/C3b/C3c). |
Immunogen |
Complement component 3 (C3) purified from human plasma. |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Clone Number |
F1-8 |
Epitope Specificity |
The antibody CAM 008-01 reacts with the 75 kd beta-chain of the human complement factor 3. |
Unit Size |
400 µL: Cat. No. CAM 008-01-04 1 mL: Cat. No. CAM 008-01-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
C3 is a central component of the complement system, consisting of a beta-chain (75 kDa) and an alpha-chain (110 kDa) connected by cystein bridges. Cleavage of C3 into C3b (177 kDa) and C3a (9 kDa) is a pivotal step in the complement activation cascade, which can be initiated by three distinct pathways—the classical, the lectin and the alternative complement pathway. |