Mouse monoclonal antibody
Anti-Complement component C3a/C3a(desArg)/C3 (human
CAT NO: GAU 017-01 | Application: ELISA, WB
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Cat. No. |
GAU 017-01 |
---|---|
Specificity |
Recognizes an epitope that is present on human C3, C3a and C3a (desArg). Does not cross-react with C4a or C5a. |
Immunogen |
Human C3a |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
718 |
Clone Number |
D17/1 |
Epitope Specificity |
GAU 017-01 recognizes different epitopes on the 9 kDa C3a than GAU 013-16. No reaction is seen with a synthetic octapeptide representing the C3a C-terminal. |
Unit Size |
400 µL: Cat. No. GAU 017-01-04 1 mL: Cat. No. GAU 017-01-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Complement C3a is an anaphylatoxin of 77 amino acid residues released by the action of the C3 convertases on the N-terminal of the alpha chain of C3. It is rapidly inactivated by serum carboxypeptidase N which removes the C-terminal arginine residue generating C3a (desArg). |