Mouse monoclonal antibody

Anti-α-calcitonin gene-related peptide (α-CGRP)

CAT NO: ABS 026-04 | Application: ELISA, IHC

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Cat. No.	ABS 026-04
Specificity	ABS 026-04 binds human α-CGRP. Based on inhibition ELISA, ABS 026-04 cross-reacts up to 12% with human β-CGRP and human amylin, while there is little (<4%) cross-reaction with rat α-CGRP.
Immunogen	Synthetic human α-CGRP
Host	Mouse
Positive Species Reactivity	Human, Rat
Negative Species Reactivity	Not determined
Isotype	IgG1/k
Gene ID	24241
Clone Number	4
Epitope Specificity	The epitope lies within residues 19-37 of human α-CGRP.
Unit Size	400 µL: Cat. No. ABS 026-04-04 1 mL: Cat. No. ABS 026-04-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	Protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	Calcitonin gene-related peptide is a 37 amino acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, in addition to a variety of other cellular effects.