Mouse monoclonal antibody, biotinylated
Anti-Complement component C3a/C3a(desArg)/C3 (human)
CAT NO: GAU 017-01B | Application: ELISA, IHC
	
      
Cat. No.  | 
        GAU 017-01B  | 
      
|---|---|
Specificity  | 
            Recognizes an epitope that is present on human C3, C3a and C3a (desArg). Does not cross-react with C4a or C5a.  | 
          
Immunogen  | 
            Human C3a  | 
          
Host  | 
            Mouse  | 
          
Positive Species Reactivity  | 
            Human  | 
          
Negative Species Reactivity  | 
            Not determined  | 
          
Isotype  | 
            IgG1/k  | 
          
Gene ID  | 
            718  | 
          
Clone Number  | 
            D17/1  | 
          
Epitope Specificity  | 
            GAU 017-01 recognizes different epitopes on the 9 kDa C3a than GAU 013-16. No reaction is seen with a synthetic octapeptide representing the C3a C-terminal.  | 
          
Unit Size  | 
            150 µL, 1 mg/mL +/- 15%. Cat. No. GAU 017-01B-015 See Certificate of Analysis for details.  | 
          
Purification  | 
            Biotinylated  | 
          
Form  | 
            Liquid  | 
          
Solvent  | 
            0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15mM sodium azide  | 
          
Conjugation  | 
            Biotin  | 
          
Storage  | 
            4-8ºC without exposure to light. No precautions necessary during handling.  | 
          
Target  | 
            Complement C3a is an anaphylatoxin of 77 amino acid residues released by the action of the C3 convertases on the N-terminal of the alpha chain of C3. It is rapidly inactivated by serum carboxypeptidase N which removes the C-terminal arginine residue generating C3a (desArg).  |