Mouse monoclonal antibody

Anti-Complement component C5a/C5a(desArg) anaphylatoxin (human)

CAT NO: GAU 025-05 | Application: ELISA, WB

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Cat. No.	GAU 025-05
Specificity	GAU 025-05 reacts with human C5a/C5a(desArg).
Immunogen	Purified human C5a
Host	Mouse
Positive Species Reactivity	Human, Baboon
Negative Species Reactivity	Not determined
Isotype	IgG1/k
Gene ID	725
Clone Number	C17/5
Epitope Specificity	GAU 025-05 binds to a neoepitope exposed on C5a/C5a(desArg). (1)
Unit Size	400 µL: Cat. No. GAU 025-05-04 1 mL: Cat. No. GAU 025-05-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	Protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	Complement C5a is generated in the circulation by the activation of complement. It is a so-called anaphylatoxin of 74 amino-acid residues generated by the action of C5 convertase, which cleaves C5 into C5a and C5b. It is rapidly inactivated by serum carboxypeptidase B, which removes the C-terminal arginine residue generating C5a(desArg). (1)