Mouse monoclonal antibody
Anti-L-Ficolin (human)
CAT NO: ABS 005-19 | Application: ELISA, WB, IP
Cat. No. |
ABS 005-19 |
|---|---|
Specificity |
ABS 005-19 reacts specifically with L-Ficolin. No cross reactivity is seen with M-Ficolin (Ficolin-1) and H-Ficolin (Ficolin-3). |
Immunogen |
Purified procaryot expressed recombinant human L-Ficolin and full-length L-Ficolin (Ficolin-2) protein. |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG2a/k |
Gene ID |
2220 |
Clone Number |
19 |
Epitope Specificity |
Not determined |
Unit Size |
400 µL: Cat. No. ABS 005-19-04 1 mL: Cat. No. ABS 005-19-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein-A/G purified, from culture supernatant |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease) (1). |