Mouse monoclonal antibody
Anti-Type V Collagen (human, dog, sheep, kangaroo, pig, rabbit, bovine)
CAT NO: CSI 006-01 | Application: ELISA, WB, IHC-P, IHC-F
Cat. No. |
CSI 006-01 |
|---|---|
Specificity |
CSI 006-01 is highly specific for type V collagen. It has been shown to have no cross-reactivity with type I, III and VI collagens by ELISA and immunoblotting. There is no evidence for cross-reactivity with other connective tissue proteins (laminin, fibronectin, elastin). |
Immunogen |
Acid-digested pepsin soluble dog type V collagen |
Host |
Mouse |
Positive Species Reactivity |
Human, Pig, Bovine, Dog, Sheep (ovine), Kangaroo, Rabbit |
Negative Species Reactivity |
Mouse, Rat, Guinea Pig, Chicken |
Isotype |
IgG2a/k |
Gene ID |
1289,397533, 537387, 480684, 101115457, 100327268 |
Clone Number |
1E2-E4/Col5 |
Epitope Specificity |
Not determined |
Unit Size |
400 µL: Cat. No. CSI 006-01-04 1 mL: Cat. No. CSI 006-01-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Type V collagen is a minor component of the connective tissue, although it is present in many different types of connective tissue. Patients with defects in the type V collagen (Ehlers-Danlos syndrome) have weakend connective tissue characterized by hyperstrechable joints and fragile, easily bruisable skin. |