Anti-Complement Component C3 (human)

CAT NO: CAM 008-01

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Product Name	Anti-Complement Component C3 (human)
Description	Mouse monoclonal antibody
Isotype	IgG1/k
Host	Mouse
Clone	F1-8
Conjugation	Unconjugated
Tested Applications	ELISA, IP, IAP

Specificity
Specificity	CAM 008-01 is specific for human complement component 3 (C3/C3b/C3c).The antibody CAM 008-01 reacts with the 75 kd beta-chain of the human complement factor 3.
Immunogen	Complement component 3 (C3) purified from human plasma.
Target	C3 is a central component of the complement system, consisting of a beta-chain (75 kDa) and an alpha-chain (110 kDa) connected by cystein bridges. Cleavage of C3 into C3b (177 kDa) and C3a (9 kDa) is a pivotal step in the complement activation cascade, which can be initiated by three distinct pathways—the classical, the lectin and the alternative complement pathway.
Gene ID	718
Species Reactivity POSITIVE	Human
Species Reactivity NEGATIVE	Not determined

Properties
Form	Liquid
Unit Size	0,4 mL and 1 mL
Concentration	1 mg/mL ±15%, See CoA for lot details
Purification	Protein A or Protein G purified
Purification Notes	BSA free
Storage buffer	0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide