Anti-H-Ficolin (human)

CAT NO: RIG 334-01

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Specificity
Specificity	RIG 334-01 reacts specifically with H-ficolin. No cross-reaction has been observed with L- or M-ficolin.
Immunogen	Recombinant human H-ficolin
Target	H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.
Gene ID	8547
Species Reactivity POSITIVE	Human
Species Reactivity NEGATIVE	Not determined

Properties
Form	Liquid
Unit Size	0,4 mL and 1 mL
Concentration	1 mg/mL ±15%, See CoA for lot details
Purification	Protein A or Protein G purified
Purification Notes	BSA free
Storage buffer	0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Product Specifications

Anti-H-Ficolin (human)

CAT NUMBER: RIG 334-01B

Anti-L-Ficolin (human)

CAT NUMBER: ABS 005-16

Anti-L-Ficolin (human)

CAT NUMBER: ABS 005-19

Anti-M-Ficolin (human)

CAT NUMBER: ABS 036-01

Anti-M-Ficolin (human)

CAT NUMBER: ABS 036-05

ELISA	RIG 334-01 reacts with recombinant H-ficolin coated directly onto the microtiter well. A sandwich ELISA for H-ficolin uses RIG 334-01 for both capture and detection. (1)
IP	RIG 334-01 can be used in immunoprecipitation. (2)