Mouse monoclonal antibody
Anti-Complement component C3a/C3a/(desArg)/C3 (human
CAT NO: GAU 013-16 | Application: ELISA, WB, IHC, IF
	
      
Cat. No.  | 
        GAU 013-16  | 
      
|---|---|
Specificity  | 
            GAU 013-16 is specific for human C3, C3a and C3a (desArg) (1) and does not cross-react with C4a or C5a. (2, 3)  | 
          
Immunogen  | 
            Human C3a  | 
          
Host  | 
            Mouse  | 
          
Positive Species Reactivity  | 
            Human  | 
          
Negative Species Reactivity  | 
            Not determined  | 
          
Isotype  | 
            IgG1/k  | 
          
Gene ID  | 
            718  | 
          
Clone Number  | 
            K13/16-5.7  | 
          
Epitope Specificity  | 
            GAU 013-16 recognizes a different epitope on the 9 kDa C3a than GAU 017-01 (2, 3). No reaction is seen with a synthetic octapeptide representing the C3a C-terminal. (2)  | 
          
Unit Size  | 
            400 µL: Cat. No. GAU 013-16-04 1 mL: Cat. No. GAU 013-16-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.  | 
          
Purification  | 
            Protein A/G purified (from culture supernatant)  | 
          
Form  | 
            Liquid  | 
          
Solvent  | 
            0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide  | 
          
Conjugation  | 
            Unconjugated BSA free  | 
          
Storage  | 
            4-8ºC without exposure to light. No precautions necessary during handling.  | 
          
Target  | 
            Complement C3a is an anaphylatoxin of 77 amino acid residues released by the action of the C3 convertases on the N-terminal of the alpha chain of C3. It is rapidly inactivated by serum carboxypeptidase N which removes the C-terminal arginine residue generating C3a (desArg).  |