Mouse monoclonal antibody
Anti-H-Ficolin (human)
CAT NO: RIG 334-01 | Application: ELISA, IP
Cat. No. |
RIG 334-01 |
|---|---|
Specificity |
RIG 334-01 reacts specifically with H-ficolin. No cross-reaction has been observed with L- or M-ficolin. |
Immunogen |
Recombinant human H-ficolin |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
8547 |
Clone Number |
FCN334 |
Epitope Specificity |
Not determined |
Unit Size |
400 µL: Cat. No. RIG 334-01-04 1 mL: Cat. No. RIG 334-01-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region. |