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Recombinant protein

Recombinant Mouse NGAL

CAT NO: SP002RA


Cat. No.

SP002RA

Purification

This product is purified full length recombinant protein without any tags, produced from E. coli

Production

E. coli

Source

Full length amino acid sequence

Unit Size, Concentration

1 mL, 1000 pg/mL +/-15%

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl, 0.5% BSA; 0.5% Tween 20; 0.0016% Phenol red; 0.1% Proclin 950

Storage

2-8°C

Background

Mouse neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, 24p3, SIP24, uterocalin and siderocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. 24p3 was observed to be dramatically upregulated in kidney cell cultures infected with SV40 (1) and subsequently identified as a lipocalin (2). Unlike human NGAL, it is an acute phase protein upregulated in the liver (3), but like its mammalian homologues it is upregulated and secreted by the kidney in response to ischemic or nephrotoxic injury (4). It is also upregulated in the involuting uterus and mammary gland. (5)