Mouse monoclonal antibody
Anti-Adrenomedullin (human)
CAT NO: ABS 027-01 | Application: ELISA, WB
Cat. No. |
ABS 027-01 |
---|---|
Specificity |
ABS 027-01 binds human adrenomedullin and shows no cross-reaction with CGRP. |
Immunogen |
Synthetic human adrenomedullin 1-52 |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
133 |
Clone Number |
1 |
Epitope Specificity |
The epitope of ABS 027-01 lies within residues 22-52. |
Unit Size |
400 µL: Cat. No. ABS 027-01-04 1 mL: Cat. No. ABS 027-01-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Human adrenomedullin is a 52 amino acid peptide (MW 6029) with the physiological effect of lowering blood pressure through vasodilatation, an effect it shares with calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP). In addition adrenomedullin has other cardiovascular effects including growth and development of both cardiovascular tissues and bone, and has effects in the central nervous system connected with the regulation of fluid balance. |