| Specificity |
ABS 027-01 binds human adrenomedullin and shows no cross-reaction with CGRP.The epitope of ABS 027-01 lies within residues 22-52. |
| Immunogen |
Synthetic human adrenomedullin 1-52 |
| Target |
Human adrenomedullin is a 52 amino acid peptide (MW 6029) with the physiological effect of lowering blood pressure through vasodilatation, an effect it shares with calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP). In addition adrenomedullin has other cardiovascular effects including growth and development of both cardiovascular tissues and bone, and has effects in the central nervous system connected with the regulation of fluid balance. |
| Gene ID |
133 |
| Species Reactivity POSITIVE |
Human |
| Species Reactivity NEGATIVE |
Not determined |
