Mouse monoclonal antibody
Anti-Adrenomedullin (human)
CAT NO: ABS 027-01
|
Application: ELISA, WB
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Product Summary
Cat. No.
ABS 027-01
Specificity
ABS 027-01 binds human adrenomedullin and shows no cross-reaction with CGRP.
Immunogen
Synthetic human adrenomedullin 1-52
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
133
Clone Number
1
Epitope Specificity
The epitope of ABS 027-01 lies within residues 22-52.
Unit Size
400 µL: Cat. No. ABS 027-01-04
1 mL: Cat. No. ABS 027-01-1
1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Human adrenomedullin is a 52 amino acid peptide (MW 6029) with the physiological effect of lowering blood pressure through vasodilatation, an effect it shares with calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP). In addition adrenomedullin has other cardiovascular effects including growth and development of both cardiovascular tissues and bone, and has effects in the central nervous system connected with the regulation of fluid balance.
Application
ELISA: The binding of ABS 027-01 to this coat is not inhibited by full-length adrenomedullin in solution up to a concentration of 1 μmol/L, but is inhibited by adrenomedullin (22-52) in solution.
WB: ABS 027-01 can be used in Western blotting.
Cat. No.
ABS 027-01
Specificity
ABS 027-01 binds human adrenomedullin and shows no cross-reaction with CGRP.
Immunogen
Synthetic human adrenomedullin 1-52
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
133
Clone Number
1
Epitope Specificity
The epitope of ABS 027-01 lies within residues 22-52.
Unit Size
400 µL: Cat. No. ABS 027-01-04
1 mL: Cat. No. ABS 027-01-1
1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Human adrenomedullin is a 52 amino acid peptide (MW 6029) with the physiological effect of lowering blood pressure through vasodilatation, an effect it shares with calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP). In addition adrenomedullin has other cardiovascular effects including growth and development of both cardiovascular tissues and bone, and has effects in the central nervous system connected with the regulation of fluid balance.
ELISA: The binding of ABS 027-01 to this coat is not inhibited by full-length adrenomedullin in solution up to a concentration of 1 μmol/L, but is inhibited by adrenomedullin (22-52) in solution.
WB: ABS 027-01 can be used in Western blotting.
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