Mouse monoclonal antibody

Anti-Complement component C3a/C3a/(desArg)/C3 (human

CAT NO: GAU 013-16 | Application: ELISA, WB, IHC, IF

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Cat. No.	GAU 013-16
Specificity	GAU 013-16 is specific for human C3, C3a and C3a (desArg) (1) and does not cross-react with C4a or C5a. (2, 3)
Immunogen	Human C3a
Host	Mouse
Positive Species Reactivity	Human
Negative Species Reactivity	Not determined
Isotype	IgG1/k
Gene ID	718
Clone Number	K13/16-5.7
Epitope Specificity	GAU 013-16 recognizes a different epitope on the 9 kDa C3a than GAU 017-01 (2, 3). No reaction is seen with a synthetic octapeptide representing the C3a C-terminal. (2)
Unit Size	400 µL: Cat. No. GAU 013-16-04 1 mL: Cat. No. GAU 013-16-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	Protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	Complement C3a is an anaphylatoxin of 77 amino acid residues released by the action of the C3 convertases on the N-terminal of the alpha chain of C3. It is rapidly inactivated by serum carboxypeptidase N which removes the C-terminal arginine residue generating C3a (desArg).