Anti-Complement component C5a/C5a(desArg) anaphylatoxin (human)

CAT NO: GAU 025-05

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Product Name	Anti-Complement component C5a/C5a(desArg) anaphylatoxin (human)
Description	Mouse monoclonal antibody
Isotype	IgG1/k
Host	Mouse
Clone	C17/5
Conjugation	Unconjugated
Tested Applications	ELISA, WB

ELISA	GAU 025-05 reacts well with C5a/C5a(desArg). A strong reaction is seen in ELISA with recombinant C5a coated onto the microtiter well. (1)
WB	GAU 025-05 can be used in Western blotting. (1)

Specificity
Specificity	GAU 025-05 binds to a neoepitope exposed on C5a/C5a(desArg).
Immunogen	Purified human C5a
Target	Complement C5a is generated in the circulation by the activation of complement. It is a so-called anaphylatoxin of 74 amino-acid residues generated by the action of C5 convertase, which cleaves C5 into C5a and C5b. It is rapidly inactivated by serum carboxypeptidase B, which removes the C-terminal arginine residue generating C5a(desArg).
Gene ID	725
Species Reactivity POSITIVE	Human, Baboon
Species Reactivity NEGATIVE	Not determined

Properties
Form	Liquid
Unit Size	0,4 mL and 1 mL
Concentration	1 mg/mL ±15%, See CoA for lot details
Purification	Protein A or Protein G purified
Purification Notes	BSA free
Storage buffer	0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide