Mouse monoclonal antibody
Anti-Complement component C9 (human)
CAT NO: ABS 004-53 | Application: ELISA
Cat. No. |
ABS 004-53 |
---|---|
Specificity |
ABS 004-53 is specific for complement factor C9. |
Immunogen |
Complement factor C9 |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
735 |
Clone Number |
C9 53 |
Epitope Specificity |
Not determined |
Unit Size |
400 µL - Cat. No. ABS 004-53-04 1 mL - Cat. No. ABS 004-53-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein-A/G purified, from culture supernatant |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Complement factor C9 is a 71kDa single-chain ellipsoid a-globular molecule of 558 amino acids including a leader sequence of 20 amino acids. C9 bind the C5b8 complex on membranes and has an unique property in forming tubular structures containing between 12 and 18 monomers, closely resembling the membrane attack complex (MAC). The primary site of synthesis is hepatocytes, secondary sites are monocytes, fibroblasts and glial cells. The normal level of C9 in plasma is 60 µg/mL, and the level is up regulated from hepatocytes by IFN-g. |