Mouse monoclonal antibody

Anti-Complement component C9 (human)

CAT NO: ABS 004-22 | Application: ELISA, WB, IHC, IF

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Cat. No.	ABS 004-22
Specificity	ABS 004-22 is specific for complement factor C9.
Immunogen	Complement factor C9
Host	Mouse
Positive Species Reactivity	Human
Negative Species Reactivity	Not determined
Isotype	IgG1/k
Gene ID	735
Clone Number	22
Epitope Specificity	Not determined
Unit Size	400 µL: Cat. No. ABS 004-22-04 1 mL: Cat. No. ABS 004-22-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	Protein-A/G purified, from culture supernatant
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	Complement factor C9 is a 71kDa single-chain ellipsoid a-globular molecule of 558 amino acids including a leader sequence of 20 amino acids. C9 bind the C5b8 complex on membranes and has an unique property in forming tubular structures containing between 12 and 18 monomers, closely resembling the membrane attack complex (MAC). The primary site of synthesis is hepatocytes, secondary sites are monocytes, fibroblasts and glial cells. The normal level of C9 in plasma is 60 µg/mL, and the level is up regulated from hepatocytes by IFN-g.