Anti-Gastric Inhibitory Polypeptide (GIP)

CAT NO: ABS 021-04

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Product Name	Anti-Gastric Inhibitory Polypeptide (GIP)
Description	Mouse monoclonal antibody
Isotype	IgG1/k
Host	Mouse
Clone	4
Conjugation	Unconjugated
Tested Applications	ELISA, IHC

ELISA	With GIP coated directly at 2 μg/mL the dilution guideline is 1/2000. In addition, ABS 021-04 binds free GIP in solution.
IHC	ABS 021-04 can be used in IHC. Please consult www.proteinatlas.org.
	Paraffin-embedded human duodenum tissue immunostained with ABS 021-04. (www.proteinatlas.org)	Paraffin-embedded human small intestine tissue immunostained with ABS 021-04. (www.proteinatlas.org)

Specificity
Specificity	ABS 021-04 binds human GIP. ABS 021-04 cross-reacts up to 10% with PACAP and human GLP-2 but <0.1% with glucagon, GLP-1 or VIP.
Immunogen	Synthetic human gastric inhibitory polypeptide
Target	Human gastric inhibitory polypeptide (GIP) is a 42 amino acid peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from approximately 50% identity for glucagon to 30% identity for GLP-2).
Gene ID	2695
Species Reactivity POSITIVE	Human
Species Reactivity NEGATIVE	Not determined

Properties
Form	Liquid
Unit Size	0,4 mL and 1 mL
Concentration	1 mg/mL ±15%, See CoA for lot details
Purification	Protein A or Protein G purified
Purification Notes	BSA free
Storage buffer	0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide