Product Summary

Cat. No.
ABS 021-04
Specificity
ABS 021-04 binds human GIP. ABS 021-04 cross-reacts up to 10% with PACAP and human GLP-2 but <0.1% with glucagon, GLP-1 or VIP.
Immunogen
Synthetic human gastric inhibitory polypeptide
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
2695
Clone Number
4
Epitope Specificity
Not determined
Unit Size
400 µL: Cat. No. ABS 021-04-04 1 mL: Cat. No. ABS 024-04-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Human gastric inhibitory polypeptide (GIP) is a 42 amino acid peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from approximately 50% identity for glucagon to 30% identity for GLP-2).

Application

ELISA: With GIP coated directly at 2 μg/mL the dilution guideline is 1/2000. In addition, ABS 021-04 binds free GIP in solution.

IHC: ABS 021-04 can be used in IHC. Please consult www.proteinatlas.org.

Paraffin-embedded human duodenum tissue immunostained with ABS 021-04. (www.proteinatlas.org)

Paraffin-embedded human small intestine tissue immunostained with ABS 021-04. (www.proteinatlas.org)

Cat. No.
ABS 021-04
Specificity
ABS 021-04 binds human GIP. ABS 021-04 cross-reacts up to 10% with PACAP and human GLP-2 but <0.1% with glucagon, GLP-1 or VIP.
Immunogen
Synthetic human gastric inhibitory polypeptide
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
2695
Clone Number
4
Epitope Specificity
Not determined
Unit Size
400 µL: Cat. No. ABS 021-04-04 1 mL: Cat. No. ABS 024-04-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Human gastric inhibitory polypeptide (GIP) is a 42 amino acid peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from approximately 50% identity for glucagon to 30% identity for GLP-2).

ELISA: With GIP coated directly at 2 μg/mL the dilution guideline is 1/2000. In addition, ABS 021-04 binds free GIP in solution.

IHC: ABS 021-04 can be used in IHC. Please consult www.proteinatlas.org.

Paraffin-embedded human duodenum tissue immunostained with ABS 021-04. (www.proteinatlas.org)

Paraffin-embedded human small intestine tissue immunostained with ABS 021-04. (www.proteinatlas.org)

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