| Specificity |
ABS 046-03 binds GLP-1(1-37), GLP-1(7-37) and GLP-1(9-37). Cross-reaction with C-terminally amidated GLP-1 is 0-16% in various circumstances.C-terminus of GLP-1(1-37), GLP-1(7-37) and GLP-1(9-37) |
| Immunogen |
Synthetic GLP-1(9-37) |
| Target |
GLP-1(7-36) amide is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far. |
| Gene ID |
2641 |
| Species Reactivity POSITIVE |
Human |
| Species Reactivity NEGATIVE |
Not determined |
