Mouse monoclonal antibody

Anti-NGAL (human)

CAT NO: ABS 062-33 | Application: ELISA

Request Price
×

Request Price

"*" indicates required fields

Name*
Consent*
This field is for validation purposes and should be left unchanged.

Product Summary

Cat. No.
ABS 062-33
Specificity
ABS 062-33 is specific for human NGAL (neutrophil gelatinase-associated lipocalin).
Immunogen
Human recombinant NGAL coupled to carrier and adsorbed to aluminum hydroxide gel.
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
3934
Clone Number
33
Epitope Specificity
Differs from those of the HYB 211 and ABS 062-14.
Unit Size
400 µL: Cat. No. ABS 062-33-04 1 mL: Cat. No. ABS 062-33-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury.

Application

ELISA: When ABS 062-14 is used as biotinylated detection antibody with ABS 062-33 as capture antibody, the assay is specific for NGAL monomer, cross-reacting <1% with NGAL homodimer.

Scientific References

1. Bangert et al (2013) The Monomer is the Major Form of NGAL in Urine and Plasma in Severe Sepsis J Am Soc Nephrol 24: 368A

Cat. No.
ABS 062-33
Specificity
ABS 062-33 is specific for human NGAL (neutrophil gelatinase-associated lipocalin).
Immunogen
Human recombinant NGAL coupled to carrier and adsorbed to aluminum hydroxide gel.
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
3934
Clone Number
33
Epitope Specificity
Differs from those of the HYB 211 and ABS 062-14.
Unit Size
400 µL: Cat. No. ABS 062-33-04 1 mL: Cat. No. ABS 062-33-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury.

ELISA: When ABS 062-14 is used as biotinylated detection antibody with ABS 062-33 as capture antibody, the assay is specific for NGAL monomer, cross-reacting <1% with NGAL homodimer.

1. Bangert et al (2013) The Monomer is the Major Form of NGAL in Urine and Plasma in Severe Sepsis J Am Soc Nephrol 24: 368A

Downloads

+

Product Specification

NGAL Product Overview

Non-hazardous statement (SDS)

Related Products

+

>

Anti-NGAL (human)

CAT. NO. ABS 062-14

>

Recombinant human monomer NGAL (rhNGAL)

CAT. NO. SP001RA

>

Anti-NGAL (human)

CAT. NO. ABS 038-15B

>

Anti-NGAL (human)

CAT. NO. ABS 062-14B

>

The NGAL Test Control Kit

CAT. NO. ST003

>

Anti-NGAL (human)

CAT. NO. ABS 038-15

×