Mouse monoclonal antibody
Anti-Pancreatic Polypeptide (human, PP)
CAT NO: ABS 030-06 | Application: ELISA, WB
Cat. No. |
ABS 030-06 |
---|---|
Specificity |
ABS 030-06 binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1%. |
Immunogen |
Synthetic human PP |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
5539 |
Clone Number |
6 |
Epitope Specificity |
Not determined |
Unit Size |
400 µL: Cat. No. ABS 030-06-04 1 mL: Cat. No. ABS 030-06-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Pancreatic polypeptide (PP) is a 36 amino acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors. |