Anti-Pancreatic Polypeptide (human, PP)

CAT NO: ABS 030-06

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Product Name	Anti-Pancreatic Polypeptide (human, PP)
Description	Mouse monoclonal antibody
Isotype	IgG1/k
Host	Mouse
Clone	6
Conjugation	Unconjugated
Tested Applications	ELISA, WB

ELISA	ABS 030-06 binds free PP in solution. ABS 030-06 reacts in ELISA with PP coated directly onto the microtiter well.
WB	ABS 030-06 can be used in Western blotting.

Specificity
Specificity	ABS 030-06 binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was<0.1%.
Immunogen	Synthetic human PP
Target	Pancreatic polypeptide (PP) is a 36 amino acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.
Gene ID	5539
Species Reactivity POSITIVE	Human
Species Reactivity NEGATIVE	Not determined

Properties
Form	Liquid
Unit Size	0,4 mL and 1 mL
Concentration	1 mg/mL ±15%, See CoA for lot details
Purification	Protein A or Protein G purified
Purification Notes	BSA free
Storage buffer	0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide