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Mouse monoclonal antibody

Anti-Pancreatic Polypeptide (human, PP)

CAT NO: ABS 030-06 | Application: ELISA, WB


Cat. No.

ABS 030-06

Specificity

ABS 030-06 binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1%.

Immunogen

Synthetic human PP

Host

Mouse

Positive Species Reactivity

Human

Negative Species Reactivity

Not determined

Isotype

IgG1/k

Gene ID

5539

Clone Number

6

Epitope Specificity

Not determined

Unit Size

400 µL: Cat. No. ABS 030-06-04 1 mL: Cat. No. ABS 030-06-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Protein A/G purified (from culture supernatant)

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Conjugation

Unconjugated BSA free

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

Pancreatic polypeptide (PP) is a 36 amino acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.