Mouse monoclonal antibody
Anti-Vasoactive Intestinal Peptide (human, bovine, porcine, rat, VIP)
CAT NO: ABS 023-02 | Application: ELISA, WB, IHC, IF
Cat. No. |
ABS 023-02 |
|---|---|
Specificity |
ABS 023-02 binds to human, bovine, porcine or rat VIP, but does not bind to PHM or PACAP. |
Immunogen |
Vasoactive intestinal peptide |
Host |
Mouse |
Positive Species Reactivity |
Human, Bovine, Pig, Rat |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
7432 |
Clone Number |
2 |
Epitope Specificity |
Not determined |
Unit Size |
400 µL: Cat. No. ABS 023-02-04 1 mL: Cat. No. ABS 023-02-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Vasoactive intestinal peptide (VIP) is a 28 amino acid peptide belonging to the secretin-glucagon family of peptide hormones. Its sequence is identical in humans, cows, pigs and rats. VIP is widely distributed in the central and peripheral nervous systems, acting as a neurotransmitter or neuromodulator. Peripherally it is involved in vaso- and bronchodilatation, smooth muscle relaxation and stimulation of secretion. Ectopic endocrine tumors secreting VIP (VIPomas) give rise to raised plasma levels of VIP and are associated with watery diarrhea, hypokalemia and achlorhydria syndrome. VIP shows high sequence homology with peptide histidine-methionine (PHM) in humans or peptide histidine-serine (PHI) in pigs or rats, present in the same precursor, and with the neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP). |
