| Specificity |
CAM 005-02 is specific for the inhibitory tract of human yENaC subunit.The epitope differs from that of CAM 003-07. |
| Immunogen |
The inhibitory peptide from the human yENaC subunit. EAESWNSVSEGKQPRFSHRIPLC corresponding to amino acid residue 139-160 of human yENaC subunit. |
| Target |
The epithelial sodium channel (ENaC) of the kidney is necessary for extracellular volume homeostasis and normal arterial BP. Activity of ENaC is enhanced by proteolytic cleavage of the y-subunit and putative release of a 43-amino acid inhibitory tract from the y-subunit ectodomain. |
| Gene ID |
6340 |
| Species Reactivity POSITIVE |
Human |
| Species Reactivity NEGATIVE |
Not determined |
