Anti-L-Ficolin (human)

CAT NO: ABS 005-19

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Specificity
Specificity	ABS 005-19 reacts specifically with L-Ficolin. No cross reactivity is seen with M-Ficolin (Ficolin-1) and H-Ficolin (Ficolin-3).
Immunogen	Purified procaryot expressed recombinant human L-Ficolin and full-length L-Ficolin (Ficolin-2) protein.
Target	L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease) (1).
Gene ID	2220
Species Reactivity POSITIVE	Human
Species Reactivity NEGATIVE	Not determined

Properties
Form	Liquid
Unit Size	0,4 mL and 1 mL
Concentration	1 mg/mL ±15%, See CoA for lot details
Purification	Protein A or Protein G purified
Purification Notes	BSA free
Storage buffer	0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Product Specifications

Anti-H-Ficolin (human)

CAT NUMBER: RIG 334-01

Anti-L-Ficolin (human)

CAT NUMBER: ABS 005-16

Anti-H-Ficolin (human)

CAT NUMBER: RIG 334-01B

Anti-M-Ficolin (human)

CAT NUMBER: ABS 036-01

Anti-M-Ficolin (human)

CAT NUMBER: ABS 036-05

ELISA	ABS 005-19 is especially well suited as detecting antibody in a sandwich ELISA in combination with ABS 005-16. Furthermore, in ELISA, ABS 005-19 reacts with recombinant L-Ficolin coated directly into the microtiter well. (1)
WB	ABS 005-19 can be used in Western blotting. (1, 2, 3)
IP	ABS 005-19 can be used in immunoprecipitation. (4)