| Specificity |
ABS 026-05 binds human α-CGRP. Based on inhibition ELISA, ABS 026-05 shows full cross-reactivity with rat α-CGRP and about 50% cross-reactivity with human b-CGRP. There is no cross-reaction with human amylin.The epitope lies within residues 1-18 of human α-CGRP. |
| Immunogen |
Synthetic human α-CGRP |
| Target |
Calcitonin gene-related peptide is a 37 amino acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, In addition to a variety of other cellular effects. |
| Gene ID |
796, 24241 |
| Species Reactivity POSITIVE |
Human, Rat |
| Species Reactivity NEGATIVE |
Not determined |
