Anti-D-dimer (human, dog)

CAT NO: ABS 015-28

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ELISA	ABS 015-028 binds free D-dimer in solution. ABS 015-028 works as a capture antibody in sandwich ELISA with biotinylated ABS 015-28 or ABS 015-22 as a detection antibody. Biotinylated ABS 015-028 works as a detection antibody in sandwich ELISA with ABS 015-22 or ABS 015-28 as a capture antibody. The combination with ABS 015-28 as a capture antibody and ABS 015-22B as a detection antibody is recommended.
WB	Due to reducing conditions in Western blotting ABS 015-28 binds the beta-chain (40kDa) of D-Dimer, and not the entire D-Dimer complex.

Specificity
Specificity	ABS 015-28 binds human D-dimer. Cross-reacts with directly coated D-monomer but not with directly coated fibrinogen.When tested in a pair with itself, with ABS 015-22 and a fibrinogen-specific polyclonal antibody, the epitope appears to relate to the neo-epitope formed by cleavage of D-dimer from fibrin.
Immunogen	Purified human D-dimer
Target	D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis.
Gene ID	2243, 475473
Species Reactivity POSITIVE	Human, Dog
Species Reactivity NEGATIVE	Not determined

Properties
Form	Liquid
Unit Size	0,4 mL and 1 mL
Concentration	1 mg/mL ±15%, See CoA for lot details
Purification	Protein A or Protein G purified
Purification Notes	BSA free
Storage buffer	0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide