Mouse monoclonal antibody
Anti-Factor XII (human, heavy chain)
CAT NO: CAM 011-05 | Application: ELISA, WB

Cat. No. |
CAM 011-05 |
---|---|
Specificity |
CAM 011-05 binds the heavy chain of human factor XII, including factor XII derivatives such as α-factor XIIa and α-factor XIIa C1-inhibitor complexes. |
Immunogen |
Affinity purified human factor XII. |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Clone Number |
10-11-5 |
Epitope Specificity |
Differs from CAM 011-37. |
Unit Size |
400 µL: Cat. No. CAM 111-05-04 1 mL: Cat. No. CAM 111-05-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Factor XII is a component in the coagulation cascade. It is a plasma glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII to a-factor XIIa, which in turn activates factor XI to factor XIa. |