Mouse monoclonal antibody

Anti-Perlecan (bovine, human)

CAT NO: CSI 001-74 | Application: ELISA, WB, IHC-F, IHC-P, AP, IP

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Cat. No.	CSI 001-74
Specificity	CSI 001-74 is highly specific for perlecan. There is no evidence for cross-reactivity with other connective tissue proteins (vitronectin, fibronectin, elastin, collagen, laminin).
Immunogen	Bovine corneal endothelial cells
Host	Mouse
Positive Species Reactivity	Bovine, Human
Negative Species Reactivity	Not determined
Isotype	IgG1/k
Gene ID	444872, 3339
Clone Number	A74
Epitope Specificity	Epitope is located in domain V
Unit Size	400 µL: Cat. No. CSI 001-74-04 1 mL: Cat. No. CSI 001-74-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	Protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	Perlecan is an extracellular matrix proteoglycan. It has a large core protein of 400-450 kDa and is often produced with heparan sulfate side chains. Perlecan is found in basement membranes where it contributes to the permeability characteristics, serves as a substrate for vascular cells and binds growth factors involved in vascular remodelling.