Mouse monoclonal antibody

Anti-Procollagen type I C-terminal propeptide (human, PICP)

CAT NO: BTE 002-08 | Application: ELISA, IP

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Cat. No.	BTE 002-08
Specificity	BTE 002-08 is specific for for native PICP from amniotic fluid.
Immunogen	PICP purified from second trimester amniotic fluid by affinity chromatography
Host	Mouse
Positive Species Reactivity	Human
Negative Species Reactivity	Not determined
Isotype	IgG1/k
Gene ID	1277
Clone Number	8
Epitope Specificity	Epitope differs from that of BTE 002-18
Unit Size	400 µL: Cat. No. BTE 002-08-04 1 mL: Cat. No. BTE 002-08-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organix matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100 kDa and the normal range in serum is 100-300μg/ml.