Mouse monoclonal antibody

Anti-Vitronectin (bovine, horse, rabbit)

CAT NO: CSI 004-18 | Application: ELISA, IHC-F, IHC-P

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Product Summary

Cat. No.
CSI 004-18
Specificity
CSI 004-18 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). The antibody inhibits integrin-mediated cell adhesion to bovine vitronectin. It can be used to probe vitronectin conformation.
Immunogen
Lysed bovine corneal endothelial cells and extracellular matrix
Host
Mouse
Positive Species Reactivity
Bovine, Rabbit, Horse
Negative Species Reactivity
Human, Sheep
Isotype
IgG1/k
Gene ID
507525, 100009128, 100059034
Clone Number
A18
Epitope Specificity
Not determined
Unit Size
400 µL: Cat. No. CSI-004-18-04 1 mL: Cat. No. CSI-004-18-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognizes fibronectin.

Application

ELISA: CSI 004-18 reacts weakly in ELISA with vitronectin coated directly onto the microtiter plate.

IHC-F: CSI 004-18 is suitable in ELISA and immunostaining of frozen PLP-fixed sections of bovine tissues.

IHC-P: CSI 004-18 is suitable in ELISA and immunostaining of frozen PLP-fixed sections of bovine tissues.

Cat. No.
CSI 004-18
Specificity
CSI 004-18 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). The antibody inhibits integrin-mediated cell adhesion to bovine vitronectin. It can be used to probe vitronectin conformation.
Immunogen
Lysed bovine corneal endothelial cells and extracellular matrix
Host
Mouse
Positive Species Reactivity
Bovine, Rabbit, Horse
Negative Species Reactivity
Human, Sheep
Isotype
IgG1/k
Gene ID
507525, 100009128, 100059034
Clone Number
A18
Epitope Specificity
Not determined
Unit Size
400 µL: Cat. No. CSI-004-18-04 1 mL: Cat. No. CSI-004-18-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognizes fibronectin.

ELISA: CSI 004-18 reacts weakly in ELISA with vitronectin coated directly onto the microtiter plate.

IHC-F: CSI 004-18 is suitable in ELISA and immunostaining of frozen PLP-fixed sections of bovine tissues.

IHC-P: CSI 004-18 is suitable in ELISA and immunostaining of frozen PLP-fixed sections of bovine tissues.

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Product Specification

Non-hazardous statement (SDS)

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