Mouse monoclonal antibody

Anti-yENaC (y−subunit epithelial sodium channel)

CAT NO: CAM 003-07 | Application: ELISA, WB, IHC-P, IHC-F

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Cat. No.	CAM 003-07
Specificity	CAM 003-07 is specific for the inhibitory tract of human yENaC subunit.
Immunogen	The inhibitory peptide from the human yENaC subunit. EAESWNSVSEGKQPRFSHRIPLC corresponding to amino acid residue 139-160 of human yENaC subunit.
Host	Mouse
Positive Species Reactivity	Human
Negative Species Reactivity	Not determined
Isotype	IgG1/k
Clone Number	3c7
Epitope Specificity	The epitope is on the inhibitory tract of human ENaC. The epitope differs from that of CAM 005-02.
Unit Size	400 µL: Cat. No. CAM 003-07-04 1 mL: Cat. No. CAM 003-07-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	The epithelial sodium channel (ENaC) of the kidney is necessary for extracellular volume homeostasis and normal arterial BP. Activity of ENaC is enhanced by proteolytic cleavage of the y-subunit and putative release of a 43-amino acid inhibitory tract from the y-subunit ectodomain.