Recombinant human monomer NGAL (rhNGAL)

SP001RA

This product is purified full length recombinant protein without any tags, produced from E. coli.

E. coli

Full length amino acid sequence

1 mL, 1000 pg/mL +/-15%

Liquid

0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl, 0.5% BSA; 0.5% Tween 20; 0.0016% Phenol red; 0.1% Proclin 950

2-8°C

Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). (2) Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. (3) Expression of NGAL in the kidney is dramatically increased by acute kidney injury.