Mouse monoclonal antibody

Anti-Gastric Inhibitory Peptide (3-42) (GIP (3-42))

CAT NO: ABS 057-25 | Application: ELISA

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Product Summary

Cat. No.
ABS 057-25
Specificity
ABS 057-25 binds human GIP (3-42).
Immunogen
Synthetic human gastric inhibitory polypeptide
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Gene ID
2695
Clone Number
25
Epitope Specificity
The epitope lies within the N-terminal region of GIP (3-42)
Unit Size
400 µL: Cat. No. ABS 057-25-04 1 mL: Cat. No. ABS 057-25-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
2-8ºC without exposure to light. No precautions necessary during handling.
Target
Human gastric inhibitory polypeptide (GIP) is a 42 amino acid peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from approximately 50% identity for glucagon to 30% identity for GLP-2).

Application

ELISA: ABS 057-25 (as capture antibody) forms a sandwich ELISA pair with ABS 054-14B (as biotinylated detection antibody) for measuring GIP. Data suggest that this matched antibody pair is the most sensitive pair for measuring GIP (3-42). The detection limit obtained with our non-optimized buffer system is up to 1 ng/mL of GIP (3-42). Cross-reaction with GIP (1-42) is around 2%.

Cat. No.
ABS 057-25
Specificity
ABS 057-25 binds human GIP (3-42).
Immunogen
Synthetic human gastric inhibitory polypeptide
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Gene ID
2695
Clone Number
25
Epitope Specificity
The epitope lies within the N-terminal region of GIP (3-42)
Unit Size
400 µL: Cat. No. ABS 057-25-04 1 mL: Cat. No. ABS 057-25-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
2-8ºC without exposure to light. No precautions necessary during handling.
Target
Human gastric inhibitory polypeptide (GIP) is a 42 amino acid peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from approximately 50% identity for glucagon to 30% identity for GLP-2).

ELISA: ABS 057-25 (as capture antibody) forms a sandwich ELISA pair with ABS 054-14B (as biotinylated detection antibody) for measuring GIP. Data suggest that this matched antibody pair is the most sensitive pair for measuring GIP (3-42). The detection limit obtained with our non-optimized buffer system is up to 1 ng/mL of GIP (3-42). Cross-reaction with GIP (1-42) is around 2%.

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Product Specification

Non-hazardous statement (SDS)

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