Mouse monoclonal antibody, biotinylated
Anti-Glucagon (human, pig, rat)
CAT NO: ABS 058-08B
|
Application: ELISA
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Product Summary
Cat. No.
ABS 058-08B
Specificity
ABS 058-08 binds human glucagon.
Immunogen
Synthetic N-terminal fragment of glucagon coupled to carrier
Host
Mouse
Positive Species Reactivity
Human, Rat, Pig
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
2641, 24952, 397595
Clone Number
8
Epitope Specificity
The epitope lies within the N-terminal half of human glucagon
Unit Size
150 µL: Cat. No. ABS 058-08B-015
1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Biotinylated
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15mM sodium azide
Conjugation
Biotin
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Glucagon is a peptide hormone of 29 amino-acid residues produced by the alpha cells of the pancreatic
islets. Its effect is to raise blood sugar as a stress hormone and counter-regulatory hormone for insulin. It
is produced by cell-type-specific processing of proglucagon, which in the alpha cells is split to form
glicentin-related pancreatic polypeptide, glucagon and major proglucagon fragment, while the same
precursor is split to form glicentin, oxyntomodulin (C-terminally extended glucagon-37), GLP-1 and
GLP-2 in the L cells of the intestinal mucosa.
Application
ELISA: ABS 058-08 (as biotinylated detection antibody) forms a sandwich ELISA pair with ABS 061-09 (as a capture antibody) for measuring glucagon.
Cat. No.
ABS 058-08B
Specificity
ABS 058-08 binds human glucagon.
Immunogen
Synthetic N-terminal fragment of glucagon coupled to carrier
Host
Mouse
Positive Species Reactivity
Human, Rat, Pig
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
2641, 24952, 397595
Clone Number
8
Epitope Specificity
The epitope lies within the N-terminal half of human glucagon
Unit Size
150 µL: Cat. No. ABS 058-08B-015
1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Biotinylated
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15mM sodium azide
Conjugation
Biotin
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Glucagon is a peptide hormone of 29 amino-acid residues produced by the alpha cells of the pancreatic
islets. Its effect is to raise blood sugar as a stress hormone and counter-regulatory hormone for insulin. It
is produced by cell-type-specific processing of proglucagon, which in the alpha cells is split to form
glicentin-related pancreatic polypeptide, glucagon and major proglucagon fragment, while the same
precursor is split to form glicentin, oxyntomodulin (C-terminally extended glucagon-37), GLP-1 and
GLP-2 in the L cells of the intestinal mucosa.
ELISA: ABS 058-08 (as biotinylated detection antibody) forms a sandwich ELISA pair with ABS 061-09 (as a capture antibody) for measuring glucagon.
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