Anti-NGAL (rat)

CAT NO: ABS 039-08

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ELISA	ABS 039-08 binds free rat NGAL in solution.
IHC	ABS 039-08 reacts with rat NGAL when used in Immunohistochemistry. (1)
	NGAL immunostaining in kidney, Formalin-fixed, paraffin-embedded tissue sections of cortical epithelial cells in the S1/S2 segments (proximal convoluted tubules) following DXR-induced acute kidney injury. Top panel, saline treatment; bottom panel, DXR treatment; X630. (1)

Specificity
Specificity	ABS 039-08 binds rat NGAL (neutrophil gelatinase-associated lipocalin).
Immunogen	Recombinant rat NGAL precursor
Target	Rat NGAL, so called because it is the ortholog of human neutrophil gelatinase-associated lipocalin (NGAL), is also called lipocalin 2, 25-kDa alpha 2-microglobulin-related protein or neu-related lipocalin. It is expressed by neutrophils and various epithelial cells, including tubular cells of the kidney. It is involved in physiological processes such as the binding of siderophore iron and tissue growth and regeneration. It is up-regulated in a variety of pathological situations including infection, inflammation, renal injury and certain adenocarcinomas.
Gene ID	170496
Species Reactivity POSITIVE	Rat
Species Reactivity NEGATIVE	Human, Pig, Dog, Mouse

Properties
Form	Liquid
Unit Size	0,4 mL and 1 mL
Concentration	1 mg/mL ±15%, See CoA for lot details
Purification	Protein A or Protein G purified
Purification Notes	BSA free
Storage buffer	0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide