Mouse monoclonal antibody
Anti-Perlecan (bovine, human)
CAT NO: CSI 001-71 | Application: ELISA, WB, IHC-F, IHC-P, AP, IP
Cat. No. |
CSI 001-71 |
---|---|
Specificity |
CSI 001-71 is highly specific for perlecan. There is no evidence for cross-reactivity with other connective tissue proteins (vitronectin, fibronectin, elastin, collagen, laminin). |
Immunogen |
Bovine corneal endothelial cells |
Host |
Mouse |
Positive Species Reactivity |
Bovine, Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
444872, 3339 |
Clone Number |
A71 |
Epitope Specificity |
Epitope is located in domain I |
Unit Size |
400 µL: Cat. No. CSI 001-71-04 1 mL: Cat. No. CSI 001-71-1 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Protein A/G purified (from culture supernatant) |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide |
Conjugation |
Unconjugated BSA free |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Perlecan is an extracellular matrix proteoglycan. It has a large core protein of 400-450 kDa and is often produced with heparan sulfate side chains. Perlecan is found in basement membranes where it contributes to the permeability characteristics, serves as a substrate for vascular cells and binds growth factors involved in vascular remodelling. |