| Specificity |
ABS 064-46 is specific for C-terminus of human oxyntomodulin. Does not cross-react with glucagon.ABS 064-46 has a different epitope specificity compared to ABS 064-23 and ABS 059-20. |
| Immunogen |
Synthetic oxyntomodulin 31-37 coupled to carrier. |
| Target |
Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa. |
| Gene ID |
2641, 14526 |
| Species Reactivity POSITIVE |
Human, Mouse, Rat |
| Species Reactivity NEGATIVE |
Not determined |
