Mouse monoclonal antibody

Anti-Oxyntomodulin (human)

CAT NO: ABS 064-23 | Application: ELISA

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Product Summary

Cat. No.

ABS 064-23

Specificity

ABS 064-23 is specific for C-terminus of human oxyntomodulin. Does not cross-react with glucagon.

Immunogen

Synthetic oxyntomodulin 31-37 coupled to carrier.

Host

Mouse

Positive Species Reactivity

Human, Mouse, Rat

Negative Species Reactivity

Not determined

Isotype

IgG1/k

Gene ID

2641

Clone Number

Epitope Specificity

ABS 064-23 has a different epitope specificity compared to ABS 059-20 and ABS 064-46.

Unit Size

400 µL: Cat. No. ABS 063-23-04 1 mL: Cat. No. ABS 064-23-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.4

Purification

protein A/G purified (from culture supernatant)

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Conjugation

Unconjugated BSA free

Storage

2-8ºC

Target

Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa.

Application

ELISA: ABS 062-33 binds human NGAL coated onto a solid phase. ABS 062-33 forms a sandwich pair with HYB 211-01, -02, ABS 038-04, -14, 15, -26 and ABS 062-14 for measuring human NGAL. When ABS 062-33 is used as a capture antibody with ABS 062-14 as a biotinylated detection antibody, the assay is specific for NGAL monomer, cross-reacting <1% with NGAL homodimer.