| Specificity |
ABS 059-20 is specific for human oxyntomodulin. Cross-reacts fully with glucagon.ABS 059-20 has a different epitope specificity than ABS 064-46 and ABS 064-23. |
| Immunogen |
Synthetic full length oxyntomodulin coupled to carrier. |
| Target |
Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa. |
| Gene ID |
2641, 14526 |
| Species Reactivity POSITIVE |
Human, Mouse, Rat |
| Species Reactivity NEGATIVE |
Not determined |
