Mouse monoclonal antibody

Anti-GLP-1(7-37) and GLP-1(7-36) amide (N-terminal specific)

CAT NO: ABS 033-10 | Application: ELISA, WB

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Cat. No.	ABS 033-10
Specificity	ABS 033-10 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(9-36)amide, glucagon and human GIP. Cross-reacts 0.25% with GLP-1(1-37), approximately 6% with human GLP-2 and approximately 50% with exendin-4. ABS 033-10 cross-reacts with Liraglutide.
Immunogen	Synthetic GLP-1(7-17)
Host	Mouse
Positive Species Reactivity	Mammalia
Negative Species Reactivity	Not determined
Isotype	IgG2a/k
Gene ID	2641
Clone Number	10
Epitope Specificity	Free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide.
Unit Size	400 µL: Cat. No. ABS 033-10-04 1 mL: Cat. No. ABS 033-10-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	Protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	Glucagon-like peptide 1(7-36)amide (GLP-1(7-36)amide) is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.